Ryousuke Akiba calls himself ES, a code name taken from a mysterious scientific experiment. Ryousuke will live to be at least two centuries old and possesses strange mental powers: He can enter people’s minds, discover their darkest secrets, even rearrange their memories so that complete strangers will treat him like family. Ryousuke acts not out of malice but for survival-wandering Tokyo for reasons known only to him. No one recognizes him for what he is . . . until Dr. Mine Kujyou, a determined researcher, meets someone who challenges everything she knows about science- ES, possessor of the Eternal Sabbath gene. But is he the only one?